After which checkpoint is the cell first committed to continue the cell cycle through M?
A) G0
B) G1
C) G2
D) S
E) previous M
Answer: B
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Biology
- Several organisms, primarily protists, have what are called intermediate mitotic organization. These protists are intermediate in what sense?
- MPF reaches its threshold concentration at the end of this stage.
- At which of the numbered regions would you expect to find cells at metaphase?
- What is the correct chromosomal condition for one daughter nucleus at telophase of mitosis?
- You have a series of cells, all of which were derived from tumors, and you first need to find out which ones are malignant. What could you do?
- For a chemotherapeutic drug to be useful for treating cancer cells, which of the following is most desirable?
- A research team began a study of a cultured cell line. Their preliminary observations showed them that the cell line did not exhibit either density-dependent inhibition or anchorage dependence. What could they conclude right away?
- What explains anchorage dependence of animal cells in vitro or in vivo?
- At the M phase checkpoint, the complex allows for what to occur?
- All cell cycle checkpoints are similar in which way?
- Which of the following most accurately describes a cyclin?
- Why do neurons and some other specialized cells divide infrequently?
- Besides the ability of some cancer cells to overproliferate, what else could logically result in a tumor?
- Cells from an advanced malignant tumor most often have very abnormal chromosomes, and often an abnormal total number of chromosomes. Why might this occur?
- A particular cyclin called cyclin E forms a complex with Cdk 2 (cyclin-dependent kinase 2). This complex is important for the progression of the cell from G1 into the S phase of the cell cycle. Which of the following statements is correct?
- Which of the following describe(s) cyclin-dependent kinase (Cdk)?
- Which of the following is true concerning cancer cells?
- Density-dependent inhibition is explained by which of the following?
- A mutation results in a cell that no longer produces a normal protein kinase for the M phase checkpoint. Which of the following would likely be the immediate result of this mutation?
- The MPF protein complex turns itself off by
- Proteins that are involved in the regulation of the cell cycle, and that show fluctuations in concentration during the cell cycle, are called
- The cyclin component of MPF is destroyed toward the end of which phase?
- Which of the following triggers the cell's passage past the G2 checkpoint into mitosis?
- Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active?
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