A plant-derived protein known as colchicine can be used to poison cells by blocking the formation of the spindle. Which of the following would result if colchicine is added to a sample of cells in G2?

A plant-derived protein known as colchicine can be used to poison cells by blocking the formation of the spindle. Which of the following would result if colchicine is added to a sample of cells in G2? 





A) The cells would immediately die.
B) The cells would be unable to begin M and stay in G2.
C) The chromosomes would coil and shorten but have no spindle to which to attach.
D) The chromosomes would segregate but in a disorderly pattern.
E) Each resultant daughter cell would also be unable to form a spindle.







Answer: C


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